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KMID : 0360220080490081289
Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 8 p.1289 ~ p.1296
Epidemiologic and Clinical Features of Uveal Melanoma in Korean Patients
Bae Jeong-Hun

Lee Sung-Chul
Koh Hyoung-Jun
Kwon Oh-Woong
Song Won-Kyung
Abstract
Purpose: To investigate the epidemiologic and clinical features of uveal melanomas in Korean patients.

Methods: The medical records of 35 patients (35 eyes) with the diagnosis of uveal melanoma between September 2004 and December 2006 were reviewed retrospectively.

Results: Of the 35 patients, 22 were males (62.9%) and 13 were females (37.1%), with a mean age at diagnosis of 48.2¡¾14.1 years (range, 24-82 years). Decreased visual acuity was the most common symptom in 23 patients (65.7%), while 6 patients (17.1%) were detected without prior symptoms. The shape of the uveal melanoma was dome-shaped in 27 eyes (77.1%) and mushroom-shaped in 8 eyes (22.9%). The mean largest basal diameter of the tumors was 9.0¡¾3.3 mm (2.4-19.0 mm), and the mean apical height was 6.2¡¾2.6 mm (1.1-13.0 mm). The tumors were classified according to their size; a small melanoma was found in 4 eyes (11.4%), a medium melanoma in 29 eyes (82.9%), and a large melanoma in 2 eyes (5.7%).

Conclusions: Uveal melanomas manifest earlier in Korean patients than in Caucasian patients. At the time of diagnosis, 33 eyes (94.3%) had small or medium melanomas that could be treated. J Korean Ophthalmol Soc 49(8):1289-1296, 2008
KEYWORD
Clinicalfeature, Epidemiology, Koreanpatients, Uvealmelanoma
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